Articles Tagged With:
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Cefepime and Enmetazobactam Injection (Exblifep)
The U.S. Food and Drug Administration has approved the combination of cefepime and enmetazobactam (FPE) for the treatment of complicated urinary tract infections (cUTIs).
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Summer Travel: News Clinicians (and Their Patients) Can Use
New science can guide us as we and our patients travel this season. Now, Infectious Disease Alert briefly reviews 13 new and in-press papers from the two main travel medicine journals.
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Does Paxlovid Help in Patients with Long COVID?
Paxlovid treatment of adults with post-acute sequelae of SARS-CoV-2 infection — also known as long COVID — was ineffective in a randomized controlled trial.
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Treatment of Invasive Aspergillosis in Solid Organ Transplant Recipients: Isavuconazole or Voriconazole?
An analysis of two retrospective cohort studies of solid organ transplant recipients with invasive aspergillosis found that isavuconazole and voriconazole had similar efficacy, but isavuconazole was better tolerated.
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Vitamin D Supplementation to Prevent Respiratory Infections?
In June 2024, the Endocrine Society released new evidence-based guidelines suggesting that all children up to 18 years of age should receive vitamin D supplements, both to prevent rickets and to prevent respiratory tract infections. However, careful review of the data suggests that widespread implementation of this recommendation might not be warranted in North America.
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Ethical Concerns for Study Participants with Opioid Use Disorder
Individuals with opioid use disorder are a vulnerable population who face some unique risks when participating in research.
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Trichinella Outbreak from Eating Bear Meat and Cross-Contaminated Vegetables
A family outbreak of trichinellosis occurred after a feast of bear meat and vegetable kabobs that was caused by a species of Trichinella that is resistant to freezing.
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Some Hospitals Still Restrict Family Presence
Many hospitals still have not lifted restrictions on family presence during resuscitation/invasive procedures that were implemented during the pandemic, raising ethical concerns. A year out from the end of the global pandemic, it is time for family presence to be reestablished to reflect a culture of patient and family-centered care, according to an updated practice alert from the American Association of Critical-Care Nurses.
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Ethical Concerns if AI Tools Assist Surrogate Decision-Makers
Surrogate decision-makers are faced with a formidable task: To make decisions based on the ethical principle of substituted judgment. “The idea is supposed to be, when these surrogates are making decisions, they are not supposed to choose what they want,” says David Wendler, MA, PhD, head of the section of research ethics in the Department of Bioethics at the National Institutes of Health Clinical Center. The surrogates instead must ask: What decision would the patient make?
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Newer Antibiotics for Resistant Gram-Negative Infections: Why Are Clinicians Not Using Them?
A retrospective cohort study on adult inpatients with difficult-to-treat resistant pathogens found clinicians used older, generic antibiotics with suboptimal safety profiles in almost 80% of cases.